M
MOTS-c
Research Use Only
Metabolic
MOTS-c
CAS: 1627580-64-6
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrial-derived peptide discovered in 2015. It has been studied as an exercise mimetic that activates AMPK, regulates metabolic homeostasis, and has shown effects on insulin sensitivity, fat oxidation, and physical performance. MOTS-c is unique among peptides in that it is encoded by mitochondrial DNA rather than nuclear DNA, representing a new class of signaling molecules.
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